Capnocytophaga infection from a dog bite chicago injury lawyer. The frequency with which these bacteria have been isolated in large patient series ranges from 0. The capnocytophaga germs that are common in dogs and cats can be spread to people through a bite or after close contact with dogs or cats. Capnocytophaga canimorsus article about capnocytophaga.
Capnocytophaga sputigena definition of capnocytophaga. Capnocytophaga sputigena bacteremia in a patient with chronic lymphocytic leukemia jungah kim, m. Capnocytophaga species are facultatively anaerobic gramnegative bacilli that are part of the normal oral flora, and it has been suggested that bloodstream infections develop when. Although capnocytophaga are gingival organisms and usually implicated as opportunists in severely ill, neutropenic patients with oral ulcerations, our patient was edentulous and without. The significance of individual species in periodontal and extraoral diseases is unclear, due to the inability of conventional phenotypic tests to identify clinical isolates to species level. Studies have shown that capnocytophaga bacteremia is associated with severe oral pathology and neutropenia, which can also result in abscess, fulminant sepsis, lung abscess, endocarditis, and meningitis 912. These organisms are part of the normal oral flora and were first described as bacteroides ochraceus and cdc group df1.
Bacteremia caused by capnocytophaga species in patients with. May 22, 20 capnocytophaga sputigena is an unusual cause of communityacquired pneumonia. Every couple of months theres a news report about a person with infection caused by the dogassociated bacterium capnocytophaga canimorsus. Capnocytophaga sputigena as separate species, and underlined the problems of distinguishing between them. Infections are more often linked to dog bites or dog contact. Detection, identification, comparison capnocytophaga. Capnocytophaga sputigena empyema journal of clinical. Capnocytophaga infection from a dog bite chicago injury lawyers.
The study confirmed capnocytophaga ochracea and capnocytophaga sputigena as separate species, and underlined the problems of distinguishing between them by conventional phenotypic tests. Capnocytophaga ochracea, capnocytophaga sputigena, and capnocytophaga gingivalis. Specific antimicrobial therapy was instituted, supplemented with corneal cryotherapy. They were the earliest bacteria to be isolated and named from the human subgingival plaque.
Primary disease is uncommon, except in children where staphylococcus aureus is the main pathogen. We report a 60yearold woman who developed a primary iliopsoas abscess as a result of haematogenous spread of capnocytophaga sputigena from a palatal fistula and chronic sinusitis due to previous treatment. However, a sterile corneal melt led to the late loss of the eye. A genus of bacteria comprising fusiform, fermentative, gramnegative rods which require carbon dioxide for growth and show gliding motility explanation of capnocytophaga canimorsus. Capnocytophaga article about capnocytophaga by the free. Most cases are caused by grampositive organisms, such as streptococci and staphylococci. We report a case of cavitary lung abscess caused by a capnocytophaga species in a patient with a metastatic neuroendocrine tumor.
Capnocytophaga canimorsus is a bacterial cause of fulminant sepsis among individuals who have been bitten by a dog. Biological and chemical characterization ofendotoxinfrom. Capnocytophaga species are known commensals of the oral cavity of humans and animals mainly dogs and cats and are a rare cause of respiratory tract infections. Capnocytophaga sputigena, belongs to the genus capnocytophaga, family. Biological and chemical characterization of endotoxin from capnocytophaga sputigena. Jun 19, 2014 capnocytophaga sputigena bacteremia in a patient with chronic lymphocytic leukemia jungah kim, m. Antibiotic content of selective culture media for isolation. Capnocytophaga canimorsus informational slideshow youtube. We present a unique case of a polymicrobial empyema, with a predominance of capnocytophaga sputigena, in an older patient with no. The characteristics of the isolates were compared with 10 fresh and 2 stock isolates of fusobacterium nucleatum. The discovery and naming of capnocytophaga canimorsus jonathan y. Assessment of five culture media for the growth and. In view of the presence of capnocytophaga sputigena, a com. The presence of two distinct clusters of oral isolates from children indicated the existence of novel species, supported by analysis of nearfulllength 16s.
Iliopsoas abscess is usually secondary to the spread of infection from a contiguous focus. Other capnocytophaga species may be part of animal oral flora, or normal human oral floradental plaques, e. Detection of a fibroblast proliferation inhibitory factor from capnocytophaga sputigena. The first group is made up of the two species located in animal oral cavities and the second one is formed by the seven human species capnocytophaga ochracea, capnocytophaga sputigena, capnocytophaga gingivalis, capnocytophaga granulosa, capnocytophaga. Diversity of capnocytophaga species in children and. Capnocytophaga ochracea is an aerotolerant anaerobe that requires either an anaerobic environment or 5% co2 concentration of the gaseous form or 20 mm hco3 in the hydrated form 7. Capnocytophaga sputigena bacteremia in a patient with. Pdf capnocytophaga sputigena bacteremia in a patient. Diagnosing capnocytophaga canimorsus infections volume.
Bacteria of the genus capnocytophaga form part of the resident oral flora in children and adults. Pcr detection of capnocytophaga species in dental plaque. Theextraction procedure yielded a lipopolysaccharide which accounted for approximately 1. An endotoxin was isolated from capnocytophaga sputigena strain 4 by a modification of.
Capnocytophaga species are facultative anaerobic, capnophilic, fusiform, gramnegative bacilli exhibiting gliding motility. Capnocytophaga sputigena is an unusual cause of communityacquired pneumonia. Biological and chemical characterization of endotoxin from. We report a 60yearold woman who developed a primary iliopsoas abscess as a result of haematogenous spread of capnocytophaga sputigena from a palatal fistula and chronic sinusitis due to previous treatment for nasopharyngeal carcinoma. Capnocytophaga species are a rare cause of bacteremia in patients with neutropenia and cancer. The word element capno in the bacteriums name refers to its ability to survive in high levels of carbon dioxide. Ninetyseven strains of capnocytophaga isolated from the oral cavity and the type strains of c.
The extraction procedure yielded a lipopolysaccharide which accounted for approximately 1. Capnocytophaga sputigena bacteremia in a neutropenic host. The genus capnocytophaga comprises a group of fastidious capnophilic, facultatively anaerobic gram. Capnocytophaga are gramnegative, facultative anaerobic bacteria. A 22yearold woman presented an amoxicillinresistant pneumonia. The discovery and naming of capnocytophaga canimorsus. Capnocytophaga sputigena bacteremia in a patient with chronic. The genus initially included three species on the basis of morphological, physiological and dna data. Bacteremia caused by capnocytophaga species in patients. To view the entire topic, please sign in or purchase a subscription official website of the johns hopkins antibiotic abx, hiv, diabetes, and psychiatry guides, powered by unbound medicine. Lin after 1961, a number of previously unidentified gramnegative bacilli were referred to the centers for disease control and prevention.
Most people who have contact with a dog or cat do not become sick. Capnocytophaga sputigena, belongs to the genus capnocytophaga, family flavobacteriaceae, is a gramnegative bacillus and a facultative anaerobic fermenter. Find out information about capnocytophaga canimorsus. Capnocytophaga definition of capnocytophaga by the free. Its a zoonotic disease passed by dogs and cats that is pretty nasty. Rarely, capnocytophaga germs can spread to people through bites, scratches, or close contact from a dog or cat and may cause illness, including sepsis. Ocular capnocytophaga infection in an edentulous, immunocomp. It is a commensal bacterium in the normal gingival flora of canine and feline species, but can cause illness in humans. Capnocytophaga infection from a dog bite chicago injury. Capnocytophaga spp consists of facultative anaerobic gram. Most of these reports dont get too much attention, but every once in a while they get picked up pretty widely, resulting in another round of questions about this strange bacterium. Antimicrobial treatment of capnocytophaga infections. The first group is made up of the two species located in animal oral cavities and the second one is formed by the seven human species capnocytophaga ochracea, capnocytophaga sputigena, capnocytophaga gingivalis, capnocytophaga.
Assessment of five culture media for the growth and isolation of. This article cites 8 articles, 0 of which can be accessed free at. Pdf capnocytophaga sputigena bacteremia in a patient with. Although occasionally found in soil and water, the predominant natural habitat of capnocytophaga species is the human oropharynx. We present a unique case of a polymicrobial empyema, with a predominance of capnocytophaga sputigena, in an older patient with no history of animal bite or splenectomy. Capnocytophaga is the name of a group of gramnegative bacteria that live in the mouth of some animals and humans. Theirstudiessuggest that this genus includes at least three distinct biogroups. An endotoxin was isolated from capnocytophaga sputigena strain 4 by a modification ofthe hotphenolwater method. Dogs are the most common household pets in the united states. Capnocytophaga canimorsus is the species most commonly involved in zoonotic.
Capnocytophaga sputigena primary iliopsoas abscess. Capnocytophaga lung abscess in a patient with metastatic. Diagnosing capnocytophaga canimorsus infections volume 12. People with a weakened immune systems who have difficulty fighting off infections for example, people with cancer or those.
In addition, they are opportunistic pathogens associated with periodontal diseases and animal bites, causing systemic infection in both immunocompetent and immunocompromised hosts 2, 3. Capnocytophaga ochracer, capnocytophaga sputigena, capnocytophaga gingivalis, capnocytophaga granulose, and capnocytophaga heamolytica. Capnocytophaga synonyms, capnocytophaga pronunciation, capnocytophaga translation, english dictionary definition of capnocytophaga. Many kinds of bacteria germs called capnocytophaga live in the mouths of dogs and cats. These organisms are also found throughout the human gastrointestinal tract as well as in the vagina. Capnocytophaga species constitute part of the normal oral microflora of humans and animals, and are often considered as opportunistic pathogens, that was confirmed by recent studies of microbial profiles using the human oral microbe identification microarray 23, 54, 128, 1. Empyema is a problem faced by clinicians worldwide. Capnocytophaga in periodontics ppt linkedin slideshare. The capnocytophaga type strains obtained from atcc used in this investigation were. Diversity of capnocytophaga species in children and description of. Our first job is to listen to and observe what our customers need, and meet those needs with quality products and services. Capnocytophaga is a genus of gramnegative bacteria. Capnocytophaga canimorsus is the main human pathogen associated with dog bites.
Capnocytophaga canimorsus formerly cdc group df2 and capnocytophaga cynodegmi cdc group df2 like were proposed as two new species 1. Keratocyst capnocytophaga superinfection rua gonzalvez. See the preventing dog bites page for information on how to prevent dog bites and what to do if you are bitten, regardless of your health status. Clinical isolates of capnocytophaga spp are classified into two broad groups. Case report our patient was a 68yearold male who had a significant past medical history only of hypertensive intracranial hemorrhages managed conservatively, vascular dementia. The genus capnocytophaga includes three bacterial species. The genus capnocytophaga is a group of fusiform, gramnegative, rodshaped organisms with gliding motility whose growth is favoured by a capnophilic atmosphere. It is epidemiologically similar to but less virulent than capnocytophaga canimorsus. Thisdesignation is aptfor all ofthese strains, andweconcurwithsocranskyetal. Sixtyeight strains of capnophilic fusiform gramnegative rods from the human oral cavity were subjected to extensive physiologic characterization, tested for susceptibility to various antibiotics, and the molpercent guanine plus cytosine of each isolate determined.
The genus initially included three species on the basis of morphological, physiological and dna. On trypticase bbl microbiology systemssoyblood agar, the cells translocated by gliding. Metagenomic analysis of the canine oral cavity, as revealed by highthroughput pyrosequencing of the 16s rrna. Detection, identification, comparison capnocytophaga, bacteroides. Organisms have a long, fusiform appearance on gram stain, making it distinctive enough to. Normally found in the oropharyngeal tract of mammals, they are involved in the pathogenesis of some animal bite wounds and periodontal diseases. Aug 03, 2018 every couple of months theres a news report about a person with infection caused by the dogassociated bacterium capnocytophaga canimorsus. It has been linked to periodontal disease, and may cause multidrug resistance and sepsis. They are recognized as opportunistic pathogens of various extraoral infections. Capnocytophaga definition of capnocytophaga by medical. What is capnocytophaga how common is capnocytophaga. Estimates predict that 50% of all americans will be bitten in their lifetime by an animal and that. Capnocytophaga species are facultative anaerobic, capnophilic, fusiform, gram negative bacilli exhibiting gliding motility.
Pmc free article stevens rh, sela mn, mcarthur wp, nowotny a, hammond bf. Capnocytophaga canimorsus is a fastidious, slowgrowing, gramnegative rod of the genus capnocytophaga. To atcc valued customers, atcc stands ready to support our customers needs during the coronavirus pandemic. Although rare, the bacteria capnocytophaga canis, which occurs naturally in dogs mouths and is estimated to be in up to 70% of dogs, can be transmitted to humans through bites, scratches, or licks that come into contact with open wounds or mucous membranes.
Transmission may occur through bites, licks, or even close proximity with animals. Quick slideshow i did for a project in medical science. A motile, nonflagellated gramnegative bacillus which is tapered at one and rounded at the other. Capnocytophaga species infectious disease and antimicrobial. Aug 15, 2001 capnocytophaga species are a rare cause of bacteremia in patients with neutropenia and cancer. There are 9 capnocytophaga species described that inhabit exclusively in the oral cavity of mammals. When examined by both light and scanning electron microscopy, capnocytophaga gingivalis, c. The genus consists of seven species, namely capnocytophaga gingivalis, c. Microscopy of capnocytophaga sputigena, capnocytophaga. In 1976, light was shed on these unidentified bacilli when bobo and newton described a man who developed septicemia and meningitis after.
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